Basically, if your machine runs Windows, it will run IES tools. You also need internet connectivity for licensing, crash reporting, online training videos and in some cases, the user's guide. The software will connect to IESCustomer.com, and softwarekey.com via secure https protocols.
We have tested products using video cards from all the major players: Intel, NVIDIA, and AMD. If you have issues, look for video card settings and also the latest driver. (They may be updated frequently.)
We see sporadic issues with the "Quadro" line of video-cards by NVIDIA. These are high-end CAD optimized cards. Usually, tweaking some of the many settings on these cards allow them to function OK with our products. All other off-the-shelf NVIDIA cards work great.